温州肯恩大学夏季科研项目专属成果上线
近日，温州肯恩大学迎来第三届夏季师生拍档科研项目（Summer Student Partnering with Faculty Research Program，简称SSpF) 成果汇报会。夏季师生拍档科研项目（SSpF）是温州肯恩大学的品牌科研活动。每年暑假，指导老师将在短暂的2个月时间里指导学生开展科研项目。
从今年4月开始，学生和老师一起申报项目，科研办（校地合作办）邀请同行评审，优中选优，选拔了13组项目。在9月开学季，这13组队伍展示了他们的阶段性研究成果。
今年的夏季师生拍档科研项目，科研办（校地合作办）还邀请来自不同领域的教授对13组项目进行了打分，并给出有针对性的专业性意见。很多教授表示他们将与学生继续深化课题内容，后续将带着科研成果参加国际会议、发表高质量文章。期待我们的项目能开出绚丽的花朵，结出丰硕的果实。
部分学生参与汇报
【2023年Summer Student partnering Faculty项目】
今年，各项目组的主题着眼于金融市场、生物环境、人工智能、心理健康等领域，对行业热点、社会关切等进行深入研究和分析，理论与实践并重，助力社会发展。
※ 优秀案例分享 ※
1. 关注青少年心理健康
Focus on Adolescent Mental Health
【Project】探究青少年与父母对抑郁症的污名化态度及其对潜在求助行为和心理健康的影响
Explore the Effect of Adolescents’ and Parents’ Stigma toward Depressive Disorder on Potential Help-Seeking Behavior and Mental Health
Instructor：Qian Li
Student：Pengmei Zhang, Mengqi Wang, Yihan Weng, Shuang Wu
摘要 Abstract<<<<
近几十年来，全球青少年抑郁症的患病率显著上升，然而，与其高患病率相矛盾的是青少年中选择向专业人士求助的比例却非常低。本研究旨在调查青少年及其父母对抑郁症的态度与他们求助行为倾向之间的关系，从而更全面地了解如何支持青少年的心理健康发展。
The prevalence of depressive disorders among adolescents has risen significantly worldwide. However, there is a considerable discrepancy between the high prevalence of depression and the low rates of help-seeking behavior. Therefore, the current study aims to investigate the association between attitudes toward depression among adolescents and their parents and their behavioral tendency to seek help in order to contribute to a more comprehensive understanding of how to support adolescents’ mental health conditions.
研究一（n = 198）从理论概念出发，设计了基于情境的量表来测量个人对抑郁症的污名化态度，并通过探索性因素分析，得到了六个维度的结构：认知层面的两个维度（即对患抑郁症个体的危险性和过错性的刻板印象），情感层面的两个维度（即对患抑郁症个体的恐惧和愤怒情绪），以及行为倾向的两个维度（包含社交隔离和歧视行为）。
In study 1 (n = 198), based on the theoretical concept of stigma, we developed a scenario-based scale to measure individuals’ stigma toward depression. Exploratory factor analysis revealed a six-factor structure, including two cognitive dimensions (i.e., stereotypes of the dangerousness and blameworthiness of individuals with depression), two affective dimensions (i.e., feelings of fear and anger toward individuals with depression), and two behavioral dimensions (i.e., social segregation and discrimination).
研究二（n = 754）中的验证性因素分析进一步证明了六维模型的拟合度较好(CFI = .935, TLI = .921, RMSEA = .068, SRMR = .063)。
In study 2 (n=754), we further validated the 6-dimensional structure and examined the psychometric properties of the scale through confirmatory factor analysis (CFI=.935, TLI=.921, RMSEA=.068, SRMR=.063).
研究三（青少年377人，父母377人）的结果表明相较于青少年群体，父母群体中针对抑郁症的污名化态度程度更高（t = 5.775, p < 0.001)，而且青少年本人 (r = -.455, p<0.001) 与其父母的污名化态度 (r = -.393, p < 0.001) 与青少年寻求专业帮助的倾向呈负相关，而且父母的污名化态度和青少年整体心理健康状况呈负相关 (r = -.102, p <0.05)。
In study 3 (377 parents and 377 adolescents), results indicated that parents tend to endorse a more stigmatizing attitude toward depression, both adolescents’ (r = -.455, p <0.001) and their parents’ stigma (r =-.393, p <0.001) are negatively correlated with adolescents’ tendency to seek professional help, and parents’ stigma are negatively correlated with adolescents’ general mental health condition (r =-.102, p <0.05).
2. 关注生态系统
Focus on the Ecosystem
【Project】狼尾草的植物修复潜力及其根际相关的微生物群落结构
Biosynthesized Zinc Oxide Nanoparticles Modulate the Phytoremediation Potential of Pennisetum Giganteum and its Rhizocompartments Associated Microbial Community Structure
Instructor：Muhammad Khalid
Student：HaoXiang Li, KeDi Li
摘要 Abstract<<<<
在当代，有机和无机污染物进入环境导致环境退化，对全球生态系统构成重大威胁（Zeeshan等，2021）。在环境污染物中，重金属（HMs）由于其持久性和累积性特点表现出较高的毒性，对生物体构成有害风险（Ali，Khan和Ilahi，2019）。
In the contemporary era, the influx of both organic and inorganic contaminants into the environment has resulted in its degradation, posing a substantial threat to the worldwide ecosystem (Zeeshan et al., 2021). Amidst environmental pollutants, heavy metals (HMs) exhibit heightened toxicity owing to their enduring and accumulative characteristics, presenting a detrimental risk to biological entities (Ali, Khan, & Ilahi, 2019).
镉（Cd）在农产品中的积累以及其可能进入食物链的潜在危险对公共健康产生严重影响。为了解决土壤镉污染问题，采用生物合成的氧化锌纳米颗粒（ZnO.NPs）和狼尾草（Pennisetum giganteum）的组合进行修复。通过在镉污染土壤（40 mg/kg）中使用低剂量（50 mg/kg）和高剂量（100 mg/kg）的ZnO.NPs促进P. giganteum植物的植物萃取潜力，并评估其对根际微生物群落的影响。
The accumulation of cadmium (Cd) in agricultural products and the potential danger of its incursion into the food chain pose serious implications for public health. To address soil Cd-contamination, a combination of biogenic zinc oxide nanoparticles (ZnO.NPs) and Pennisetum giganteum was employed for remediation. Phytoextraction potential of P. giganteum plants was assessed in Cd-contaminated soil (40 mg/kg) by facilitating with low (50 mg/kg) and high (100 mg/kg) dosages of ZnO.NPs and its impact was assessed on the indigenous microbial community associated with its rhizocompartments.
与对照组相比，ZnO.NPs显著提高了植物在植物茎部（1.48-1.72倍）和根系（1.6-2.1倍）中富集镉的耐受性和能力。此外，还观察到了抗氧化反应的改善，在ZnO.NPs低浓度下，有效减轻了氧化应激，这得以通过叶片超微结构分析得到证实。此外，土壤酶活性，如酸性磷酸酶（1.33倍和1.43倍）、脲酶（1.42倍和1.57倍）、过氧化氢酶（2.3倍和1.9倍）和蔗糖酶（1.2倍和1.3倍），分别受到低剂量和高剂量的增强。此外，我们选择研究植物根际相关的细菌群落结构，这可能受到ZnO.NPs影响的土壤酶的改变的影响。多元分析表明，在对照组、低剂量和高剂量的ZnO.NPs处理下，根际相关的细菌群落显著不同。然而，细菌群落结构的丰富度和均匀度没有显著差异，而多样性仅受高浓度的ZnO.NPs的负面影响。值得注意的是，只有在低浓度ZnO.NPs的植物中才显著富集了Thiobacillus、Stenotrophomonas、Chloroflexi、Cellvibro和Phenylobacterium等菌属。对指示菌属的深入分析也表明，不同处理下植物根际部位存在差异（LDA得分 > 2.0，p < 0.05）。
ZnO.NPs substantially enhanced the tolerance and ability of plant to accumulate Cd in plant shoot (1.48-1.72-fold) and root (1.6-2.1-fold) system as compared with control. Moreover, an improvement in the antioxidative response was observed, which effectively mitigated oxidative stress at a low concentration of ZnO.NPs, as evidenced by leaf ultrastructural analysis. Beyond that, soil enzyme activities such as acid phosphatase (1.33 and1.43-fold), urease (1.42 and 1.57-fold) catalase (2.3 and 1.9-fold) and saccharase (1.2 and 1.3-fold) were augmented by low and high doses, respectively. In addition, we opted to examine the plant rhizocompartments-associated bacterial community structure which likely affected by the modifications in soil enzymes influenced by ZnO.NPs. Multivariate analysis demonstrated that root associated bacterial community was prominently differed in control, low and high levels of ZnO.NPs. Nevertheless, the bacterial community structure’s richness and evenness did not show significant differences, while diversity was found to be negatively affected only by high concentrations of ZnO.NPs. It is worth noting that, Thiobacillus, Stenotrophomonas, Chloroflexi, Cellvibro and Phenylobacterium were significantly enriched only in low ZnO.NPs supplemented plants. In-depth analysis of indicator genera also indicated differences (LDA score > 2.0, p < 0.05) in plants rhizocompartments under different treatments.
本研究的结果突出显示了几个植物纳米材料的显著变化，特别是在低浓度下，通过提高植物修复能力、整体表现和根际相关的细菌群落结构。
The results from this study highlight significant changes in several plant-based endpoints, particularly at low concentration, by improving the phytoremediation potential, overall plant performance and rhizocompartments-associated bacterial community structure.
温州肯恩大学学术事务副校长 杨毅欣博士
温州肯恩大学学术事务副校长杨毅欣博士为本次成果汇报会致辞。杨校长对学生和教授们在炎热的暑期期间仍能坚持在校进行学术研究致以真挚的敬意。他向在场的学生和教师讲述了近年来温肯取得的巨大科研成效和快速发展趋势。
杨校长期望通过SSpF项目，鼓励温肯学生进行跨学科研究，发挥主动创造性，培养对科研的兴趣与爱好，成为真正的 “X” 复合型人才。
为鼓励学生和教授一起开展学术研究，支持教学理论实践化，温州肯恩大学自2015年开始实施师生拍档科研项目（Student Partnering with Faculty Research Program，简称SpF），对入选的项目给予一定资金支持。项目的实施极大地提升了学生的科研综合素质和能力，促进课堂教学的实践化和成果化。
截至2023年，共有541名学生，130名指导老师参与了SpF，累计获得资助资金近522万元。SpF支持学生参加了80多场国内外学术会议并现场展示研究成果，师生在具有影响力的国际期刊上发表论文160余篇。
每年暑假，指导老师和学生利用8周的时间，开展探索和研究，合作完成科研项目。自2021年开始至今，共有近100名学生，26位指导老师，参加SSpF，学校共资助了近115万元。
随着SpF/SSpF/SpS,学生学术科研日等项目、活动的不断地推进，更多的学生和老师参与进了学校的学术科研工作中，利用所学知识，在国际化的环境和视野下，拓展科研边界，为社会各领域提供服务和支持。
来源：温州肯恩大学
